Trimethylsilyl Cyanide TMSCN CAS 7677-24-9 Assay ≥97.0% (GC)

Short Description:

Chemical Name: Trimethylsilyl Cyanide

Synonyms: TMSCN 

CAS: 7677-24-9

Appearance: Colorless to Light Yellow Liquid

Assay: ≥97.0% (GC)

High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Trimethylsilyl Cyanide (TMSCN) (CAS: 7677-24-9) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com 

Chemical Properties:

Chemical Name Trimethylsilyl Cyanide
Synonyms TMSCN; Cyanotrimethylsilane; Trimethylsilylformonitrile; Trimethylsilylcarbonitrile 
CAS Number 7677-24-9
CAT Number RF-PI307
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C4H9NSi
Molecular Weight 99.21
Melting Point  8.0~11.0℃(lit.)
Boiling Point  114.0~117.0℃(lit.)
Solubility Miscible With Organic Solvents
Sensitive Moisture Sensitive, Heat Sensitive
Water Solubility Reacts
Stability Stable Under Room Temperatures and Pressures
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Colorless to Light Yellow Liquid
Assay / Analysis Method ≥97.0% (GC) 
Density (20℃)  0.793~0.798
Refractive Index n20/D 1.391~1.393
Infrared Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediate

Package & Storage:

Package: Bottle, Barrel, 25kg/Barrel, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.

Advantages:

1

FAQ:

Application:

Trimethylsilyl Cyanide (TMSCN) (CAS 7677-24-9) is a commercial reagent used as cyanide source for nucleophilic reactions. It was first synthetized by the reaction of trimethylsilicon halides TMSX and AgCN in 1952. TMSCN is a versatile reagent that can be used in several different reactions, but it is generally used in nucleophilic additions to aldehydes, ketones and imines to form cyanohydrin silyl ethers (Scheme 1a) and α-aminonitriles in Strecker-type reactions (Scheme 1b). Trimethylsilyl Cyanide is a highly versatile reagent that reacts with a multitude of functional groups to yield an array of products and/or highly valuable synthetic intermediates. Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. Trimethylsilyl Cyanide is an important cyanation reagents for organic synthesis, fine chemical raw materials, pharmaceutical intermediates and API.  

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